Whether the Controlled Substance Analogue Enforcement Act, 21 U.S.C. § 813, is void for vagueness as applied to synthetic cannabinoid XLR-11; and

Whether a conviction under the Continuing Criminal Enterprise statute, 21 U.S.C. § 848, may stand when the Applicants' co-defendant and purported supervisee was acquitted at the same trial on the predicate offenses.

Whether the Ninth Circuit correctly applied the standard for reviewing a federal criminal conviction in light of alleged constitutional violations