Can a defendant who claims actual innocence after entering a plea agreement be barred from raising his actual innocence claim based on a Plea Agreement Waiver?

Does a fatally deficient indictment overcome a Plea Agreement waiver to restrict a defendant's ability to collaterally attack his conviction?

Can a Commerce Clause regulation be maintained as Constitutional under the aggregate market effect of Gonzales v. Raich when it is shown that there is no National Market to effect?

actual-innocence,plea-agreement,waiver,indictment,collateral-attack,commerce-clause,gonzales-v-raich